A Novel protocol for synthesis of Hantzsch 1, 4- dihydropyridines using PEG-400 as a reaction medium and under catalyst-free condition

نویسندگان

  • Ali Ezabadi Department of Chemistry, Faculty of Sciences, Islamic Azad University, Central Tehran Branch, Iran
  • Fatemeh Tosan Department of Chemistry, Faculty of Sciences, Islamic Azad University, Central Tehran Branch, Iran
چکیده مقاله:

An efficient and expeditious catalyst-free procedure was developed for the one- pot synthesis of 1, 4-dihydropyridine derivatives via the three-component reaction of various aldehydes, ethyl acetoacetate, and ammonium acetate in PEG-400. The reaction was carried out at 110°С and the products were obtained in good to high yields.

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منابع مشابه

Novel procedure for preparation of Hantzsch 1, 4- dihydropyridines using PEG-400 as a reaction medium and under catalyst-free condition

An efficient and expeditious catalyst-free procedure was developed for the one- pot synthesis of 1, 4-dihydropyridine derivatives via the three-component reaction of various aldehydes, ethyl acetoacetate, and ammonium acetate in PEG-400. The reaction was carried out at 110°С and the products were obtained in good to high yields.

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عنوان ژورنال

دوره 8  شماره 3

صفحات  5- 11

تاریخ انتشار 2018-10-15

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